Showing posts with label chest cavity. Show all posts
Showing posts with label chest cavity. Show all posts

Saturday, August 22, 2009

Asbestos Related Mesothelioma Cancer :: Blood Test

Asbestos Cancer Mesothelioma is a malignant disease to take a lot of lifes each year, many people concentrate their effort in to know o find out a cure for this disease, and in other economic aspect of the asbestos, such as money compensation.

However, last researches to point out that a blood test could help screen for pleural mesothelioma by checking the blood for high levels of a protein called osteopontin, because blood esteopontin levels rise dramatically in the early stages of pleural mesothelioma, this kind of cancer is a deadly asbestos related illness.

The pleural mesothelioma is a rare disease of the lining of the lung and chest cavity that is usually cancerous, the cause is asbestos exposure and it could take 15 to 35 years to develop the disease, from the time of asbestos exposure.

The above exposure can be direct with the substance or second-hand with a family member whose clothing or skin carried the asbestos into the home. Obviously in the last case the development of the disease could take more than 35 years.

To say, the pleural mesothelioma was so difficult to detect its in early, high mortality rate and a life expectancy of few months, but with the new blood test there are higher percentage of probabilities to detect this kind of cancer, moreover its can detect or determine other kinds of asbestos related cancer. But in the letter case the findings need further study, other kind of cancer to could be early detected for osteopontin blood test is for instance "Ovarian Cancer".

So, the earlier to pleural mesothelioma cancer is detected, the better and if you want to know how to do it, a blood test could be very useful in this case, and don?t forget it, "Osteopontin".

Author: Hector Milla

Saturday, August 8, 2009

:: MESOTHELIONMA :: TREATMENT :: SURGERY ::

Surgery is an important step in confirming and knowing the nature of the cancer. It can be conducted on patients with the combination of adjuvant chemotherapies and radiations, before and after the surgery.

Pleurectomy:
The most common surgery for Mesothelioma treatment is pleurectomy, in which doctors open the patient's chest and remove the excessive fluid or tumor from the lining of the lungs (pleura). Although this procedure controls the accumulation of fluid and decreases pain, it still is not a cure. On the other hand, if the tumor is in its initial form and has not extensively grown, a pleurectomy can increase the survival rate of a patient when combined with chemotherapy and radiation. Additionally, a pleurectomy can be performed on patients with less-approving health conditions and has lower mortality rate than the extrapleural pneumonectomy.

Extrapleural Pneumonectomy (EPP):
Extrapleural pneumonectomy (EPP) is an invasive and severe form of surgery conducted on patients with Mesothelioma. In this treatment, parts of the lungs, the pleura (the lining of the lung), the pericardium (lining of the heart) and the hemi-diaphragm, along with the tumor cells, are removed. It decreases the progression of Mesothelioma, while allowing a patient to breathe smoothly. It is usually conducted on patients with early stages of the cancer and when the tumor is in chest cavity. EPP is recommended for patients with good heart and lungs conditions, in order to endure the severities of the post-operative term. Though the surgery combined with chemotherapy and radiation gives promising results, it does not guarantee a cure. Researches have shown that patients treated with extrapleural pneumonectomy and therapies have a medium life span of 35 months after the surgery, compared to only 9 months of pleurectomy. Still, some doctors question the surgery for its high risks, which include internal bleeding, blood clotting, pneumonia, amassing of pus, respiratory failure and even death. Thus, many surgeons recommend the idea of pleurectomy instead of the technically complicated EPP.

Thoracentesis:
A minor surgery is often conducted on patients who cannot undergo EPP or pleurectomy, called thoracentesis. In thoracentesis, a thoracic surgeon inserts a needle into a patient's chest to remove the excessive fluid built up in the lining of the lungs (pleura). This method neither cures nor decreases the cancer, but rather alleviate the painful symptoms of Mesothelioma. In some cases, talc or other agents are infused into a patient's chests to scar the chest wall and help them breathe properly without letting the tumor to increase, to some extent.

Paracentesis:
Paracentesis is a similar method of using a needle to extract fluid, but from the abdominal section of the body. It follows the same procedure of extracting fluid from the lining of the stomach or other abdominal organs. Patients with peritoneal Mesothelioma can benefit from paracentesis surgery.

Author: Jennifer White

Thursday, August 6, 2009

:: Malignant mesothelioma ? The cancer of the mesothelial cells ::

Mesothelium is the protective tissue that covers the chest cavity, abdominal cavity and the cavity around the heart and also produces a special lubricating fluid that allows the internal organs of the body to move around. Malignant Mesothelioma can be defined as the cancer of the mesothelial cells which become abnormal and start dividing without any order. Majority of the mesothelioma patients have a prior history of exposure to asbestos.

Types of malignant Mesothelioma
Malignant Mesothelioma or simply Mesothelioma can be divided into 3 main types namely
- Epithelioid
- Sarcomatoid
- Mixed/biphasic

Of these, Epithelioid is the most common (50% to 70% cases) and stands the best chance of recovery. Sarcomatoid type is seen in 7% to 20% cases whereas mixed/biphasic type is seen in 20% to 35% cases.

Approximately, ? of the total cases of Mesothelioma originates in the chest cavity (pleura) and is known as pleural mesothelioma. The cancer affecting the lining of the abdomen (peritoneum) is called the peritoneal mesothelioma and that affecting the "sac like" space around the heart (pericardial cavity) is called the pericardial mesothelioma. Mesothelioma at times also affects the covering layer of the testicles. However, the last two types of cases are quite rare.

Diagnosis of malignant Mesothelioma
The tumors of the mesothelium can either be benign (non cancerous) or malignant (cancerous). So whenever there are symptoms like shortness of breath, pain in chest/abdomen or swelling in the abdomen, you should consult your doctor immediately.

After the initial X-rays and scans, the doctor may look inside the chest cavity (in case of pleural tumor) with an instrument called thoracoscope and the test is called thoracoscopy. In case of tumor in peritoneum the doctor may go for peritoneoscopy with the help of a tool called peritoneoscope. Finally, if the abnormal tissue is found then a biopsy is done, whereby a piece of the unnatural tissue is cut out and placed under microscope for examination.

After the confirmed diagnosis of Mesothelioma it is also essential to ascertain its stages i.e. whether it is in localized stage or in advanced stage. In the localized stage, the cancer is found in the lining of the chest cavity or in the diaphragm or the lung. Advanced malignant Mesothelioma can again be divided into 3 stages namely stage II, III and IV. In stage II, the cancer spreads beyond the chest lining to lymph nodes and in stage III it spreads into chest wall, center of the chest, heart, through the diaphragm or abdominal lining, etc. The final or the fourth stage is the one in which the cancer has already spread to distant organs.

Treatment
Depending on the stage of the cancer, its location and the health, age and medical history of the patient, 3 types of treatments are mated out to malignant Mesothelioma patients ? surgery (to remove the tumor), radiation therapy (application of high energy rays) and chemotherapy (usage of combination of drugs). This apart, if there is any accumulation of fluid in the chest or abdomen, then the doctor needs to drain it out and the process is regarded as thoracentesis and paracentesis respectively.

So be aware of the disease, such that you can prevent it at the very onset.

Author: Fred Lindell

:: Mesothelioma: Facts about Mesothelioma ::

Mesothelioma is a form of cancer that affects the mesothelial cells of the body. These are the cells that make up the outer lining for the body"s major organs, such as the heart, lungs and stomach. These linings are referred to as the mesothelium and this is how the cancer got its name.

Pleural Mesothelioma
The pleura is the tissue that covers and lines the lungs. These are referred to by the medical community as pleural membranes. The pleura are fibrous membranes and the space between them is the pleural space. The pleural protect the lungs by producing a lubricant that fills the pleural space. This lubricant also allows the lungs to move easily within the chest cavity as we inhale and exhale.

Pleural mesothelioma is the most common type of the disease. Since the lungs are so close to the heart, it is almost always affected. The pericardium is the lining found on the outside of the heart and allows it to move freely within the heart cavity.

The Peritoneum
The peritoneum is the tissue lining the abdomen. Its job is to protect the abdomen"s contents. It produces a fluid that acts as a lubricant so organs within the abdomen may move freely. Peritoneal mesothelioma is cancer of the tissue that lines the abdominal cavity. This form of mesothelioma is more rare than pleural mesothelioma.


Causes of Mesothelioma
Mesothelioma is caused by unprotected exposure to asbestos and affects those who were put at risk for the last 50 years.


Who Gets Mesothelioma
The disease is most common in males who are between the ages of 60 and 70 years old. These men were constantly exposed to asbestos dust and fiber, which caused the mutation of the mesothelioma cells. Mesothelioma takes years to develop, which means early diagnosis is almost impossible.

Others at risk for mesothelioma are those who lived in the same household with someone who was constantly exposed to asbestos. Men carried asbestos dust and fibers into their homes on clothing. It was then breathed in by family members. This put them at risk of contacting mesothelioma and other diseases related to asbestos years after the fact.

Treatment
The success of treatment for mesothelioma isn"t high. The final stages of the disease are fatal. The earlier mesothelioma is diagnosed, the better the prognosis.

If you or a member of your immediate family has ever been constantly exposed to asbestos in the workplace, be sure to contact your health care professional to find out exactly what your options are. You may be tested for the disease and get a clear bill of health.

Author: Daniel Bell

:: Symptoms of Mesothelioma ::

In most cases, people usually ignore the symptoms of Mesothelioma due to their generic nature. This is because the early symptoms of mesothelioma can also be the indication of other common diseases. Furthermore, researches have concluded that a patient with prior exposure to asbestos may develop mesothelioma much later in his/her life, i.e. after 20 to 40 years of asbestos encounter. Thus, many patients disregard the possibility of developing mesothelioma due to something that happened much earlier in their lives.

Mesothelioma is a cancer in which the protective linings of the body’s internal organs get affected by malignant cells. These linings include:

•Pleura: the outer lining surrounding the lungs and chest cavity;
•Peritoneum: the lining of the abdominal cavity; and
•Pericardium: a sac holding the heart.

The symptoms of mesothelioma affecting these organs can vary due to the special nature and functions of the organs. Some of these symptoms are severe, and also some of the symptoms are rare. It is, therefore, recommended to contact a physician if the symptoms prevail.
Additionally, if mesothelioma is detected at early stages, the chances for a possible cure are high.

Following are the symptoms of mesothelioma, categorized by types:

Pleural Mesothelioma Symptoms:

•Shortness of breath
•Coughing up blood
•Pain in chest
•Pleural effusions (fluid accumulation in the lung lining)
•Back pain
•Hoarseness
•Weakness
•Problem in swallowing
•Loss of appetite
•Weight loss
•Excessive coughing
•Swelling
•Paralysis
•Fever

In severe cases, a pleural mesothelioma patient can develop pneumothorax or lung cancer (lung failure). Nonetheless, some patients may show almost no symptoms.

Peritoneal Mesothelioma Symptoms:

•Swelling or mass accumulation in the abdomen
•Weight Loss
•Abdominal pain
•Bowel obstruction
•Blood clots
•Fever
•Nausea
•Vomiting
•Hernia

Pericardium Mesothelioma Symptoms:

•Chest pain
•Shortness of breath
•Cough
•Unusual heart beating
•Irregular breathing patterns

These symptoms of mesothelioma can also be the indications of other minor diseases. However, if diagnosed soon, these symptoms can help the doctors to cure the cancer at a primitive stage. Remember that only a doctor can confirm the presence of mesothelioma by examining medical reports, asbestos exposure history, MRI and/or CT scan. In some cases, a needle biopsy can also be conducted.

Author: Jennifer White

What is mesothelioma..?

"Mesothelioma" is the term used to describe a cancerous tumor that involves the mesothelial cells of an organ. Mesothelial cells are cells that form a protective lining over the lungs, heart and abdominal organs. The most common type of mesothelioma is pleural mesothelioma. The pleura is a thin membrane found between the lungs and the chest cavity. It provides a lubricated surface so that the lungs do not rub and chafe against the chest walls.

What causes it?
Virtually all cases of mesothelioma are related to inhaling of asbestos fibers. There are about 3,000 cases per year (mostly men over the age of 40) and there will be about 300,000 cases before 2030. Mesothelioma usually spreads rapidly through the mesothelial cells to the heart and abdominal organs. The life span is typically 24 months after diagnosis, but it depends on what stage the cancer is detected, the health of the patient and other factors.

Although asbestos exposure causes mesothelioma, it has a latency period after exposure that could last 15 to 50 years. This means that someone who worked in a factory with asbestos 40 years ago could be developing mesothelioma now. Anyone who knows they were exposed to loose asbestos fibers should be tested regularly for mesothelioma.

Diagnosis
The onset of mesothelioma is usually very slow. The first symptom is a constant pain in the chest. This pain is later accompanies by difficulty breathing due to an accumulation of fluid in the chest. Other symptoms include coughing, fever and weight loss. Mesothelioma can be diagnosed by your doctor with a chest CT-scan.

Prognosis (the outcome)

Mesothelioma advances in 4 stages:

Stage I - the tumor is limited to the area of the lining of the lung and usually limited to only one side of the chest.
Stage II - the tumor extends to other organs within the chest cavity, such as the heart or lymph nodes in the chest.
Stage III - the tumor expands to the other side of the chest or it spreads into the abdominal organs. The lymph nodes outside the chest are affected.
Stage IV -the cancer spreads to different parts of the body far outside the chest area (liver, brain, bone, etc...).

Mesothelioma is an extremely deadly disease. The average survival time is about one year from date of diagnosis. About 20% of patients who find their cancer early and treat it aggressively will reach the five-year mark.

Author: andrew mills



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